Nuclear Magnetic Resonance Laboratory

About the Laboratory

Nuclear magnetic resonance spectroscopy is a non-desctructive interdisciplinary technique. Typical researchers come from a wide range of disciplines such as chemistry, geology, biochemistry, biology, pharmacy, or engineering. The technique has many useful applications:

  • structural connectivity of atoms within molecules
  • spacial orientation of atoms within molecules
  • solids
  • metabolomics
  • diffusion constants in solution
  • molecular relaxation characteristics
  • kinetic parameters of molecular exchange and interchange

This laboratory has three 500 MHz spectrometers and one 600 MHz spectrometer.

Laboratory Contact

Location:

500MHz NMR

G89

600MHz NMR

G93

Phone Number:

500MHz NMR

(306) 966-1710

600MHz NMR

(306) 966-1713

Laboratory Managers:

Jianfeng (Peter) Zhu

Kyle Fransishyn

 

Instruments In Lab

The Bruker Avance 500 MHz spectrometer is a 3-channel NMR system, equipped with a BACS-60 sample changer and variable temperature capability. A Bruker 5mm TXI probe is usually installed. Therefore, it is not preferable for C-13 observing experiments.

The Bruker Avance III HD 500 MHz spectrometer is a 3-channel NMR system, equipped with an Agilent HPLC for separation of mixtures and then acquiring NMR data of the fractions (LC-NMR). It is also equipped with a Bruker HR-MAS probe and a DOTY CP/MAS probe. A Bruker 5mm BBFO probe is usually installed, tunable to most BB-channel nuclei (including F-19).

The Bruker Avance 500 MHz spectrometer is a 2-channel NMR system, equipped with a SampleXpress-60 sample changer. It runs Automation NMR experiments via IconNMR, with a Bruker 5mm BBO probe.

The Bruker Avance III HD 600 MHz spectrometer is a 3-channel NMR system, equipped with a SampleCase-24 sample changer and variable temperature capability. A Bruker 5mm BBO probe is usually installed, tunable to most BB-channel nuclei (excluding F-19).

Laboratory Training

Learning to use one of the manually operated NMR spectrometers is analogous to learning to fly a jet fighter! Not what one usually does without having at least learned to fly a small plane. We recommend starting on the autosampler instrument and then graduating to one of the other spectrometers. There is much to learn and it is best done in small bits. Please contact Dr. Jianfeng Zhu to arrange a training session.

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