Nuclear Magnetic Resonance Laboratory
About the Laboratory
Nuclear magnetic resonance spectroscopy is a non-desctructive interdisciplinary technique. Typical researchers come from a wide range of disciplines such as chemistry, geology, biochemistry, biology, pharmacy, or engineering. The technique has many useful applications:
- structural connectivity of atoms within molecules
- spacial orientation of atoms within molecules
- solids
- metabolomics
- diffusion constants in solution
- molecular relaxation characteristics
- kinetic parameters of molecular exchange and interchange
This laboratory has three 500 MHz spectrometers and one 600 MHz spectrometer.
Laboratory Contact
Location:
500MHz NMR |
G89 |
600MHz NMR |
G93 |
Phone Number:
500MHz NMR |
(306) 966-1710 |
600MHz NMR |
(306) 966-1713 |
Laboratory Managers:
Instruments In Lab
The Bruker Avance 500 MHz spectrometer is a 3-channel NMR system, equipped with a BACS-60 sample changer and variable temperature capability. A Bruker 5mm TXI probe is usually installed. Therefore, it is not preferable for C-13 observing experiments.
For more detailed information, click here
The Bruker Avance III HD 500 MHz spectrometer is a 3-channel NMR system, equipped with an Agilent HPLC for separation of mixtures and then acquiring NMR data of the fractions (LC-NMR). It is also equipped with a Bruker HR-MAS probe and a DOTY CP/MAS probe. A Bruker 5mm BBFO probe is usually installed, tunable to most BB-channel nuclei (including F-19).
For more detailed information, click here
The Bruker Avance 500 MHz spectrometer is a 2-channel NMR system, equipped with a SampleXpress-60 sample changer. It runs Automation NMR experiments via IconNMR, with a Bruker 5mm BBO probe.
For more detailed information, click here
The Bruker Avance III HD 600 MHz spectrometer is a 3-channel NMR system, equipped with a SampleCase-24 sample changer and variable temperature capability. A Bruker 5mm BBO probe is usually installed, tunable to most BB-channel nuclei (excluding F-19).
For more detailed information, click here
Laboratory Training
Learning to use one of the manually operated NMR spectrometers is analogous to learning to fly a jet fighter! Not what one usually does without having at least learned to fly a small plane. We recommend starting on the autosampler instrument and then graduating to one of the other spectrometers. There is much to learn and it is best done in small bits. Please contact Dr. Jianfeng Zhu to arrange a training session.Introduction to TopSpin
Training Resources
Online courses
- Professor James S. Nowich (UC Irvine), Organic Spectroscopy
- Dr. James Keeler (Cambridge), Understanding NMR Spectroscopy
- Professor Malcolm Levitt et al., Spin Dynamics (solid state NMR)
- Dr. Joseph P. Hornak (RIT), The Basics of NMR
- Professor Hans J. Reich (Wisconsin), Structure Determination Using NMR.